(1) Induced excretion:
① Clomiphene. Take 50 mg orally daily for 5 days starting from the 5th day of the menstrual cycle. Ovulation occurs 5 to 11 days after stopping the drug. If it is ineffective, the dose can be increased to 0.1 to 0.15 grams per day.
② Chorionic gonadotropin: Often used in combination with clomiphene and discontinued after clomiphene About 7 days later, chorionic gonadotropin is added, 200 to 5000 international units each time, intramuscularly, and administered when the follicles are nearly mature to induce ovulation.
③ Urinary gonadotropin: Daily intramuscular injection of urinary gonadotropin from the 6th day of the menstrual period 1 tube of gonadotropin, used continuously for 7 days, follicle development needs to be monitored, and urinary gonadotropin should be discontinued once the follicles mature. Add 5,000 to 10,000 international units of chorionic gonadotropin intramuscularly 24 to 36 hours after stopping the drug to promote ovulation and lutein production.
④Estrogen: For women with a certain level of estrogen in their ovaries, estrogen pulse therapy can be used , around the 10th day of the menstrual cycle, take 5 mg of diethylstilbestrol orally, once every 6 hours, for a total of 20 mg. If there is a gastrointestinal reaction, 10 mg of estradiol benzoate can be used instead and injected intramuscularly once on the 10th day of the menstrual period for 3 consecutive cycles.
⑤Progesterone:Norethindrone or medroxyprogesterone acetate (medroxyprogesterone) 10 mg each time, taken orally once a day, starting on the 21st day of the menstrual cycle, for 5 consecutive days.
⑥Estrogen + progesterone: Beginning on the 5th day of the menstrual cycle, daily oral administration of alkynes nordone 5 mg and ethinylestradiol 0.03 mg,Take it continuously for 22 days, and a course of treatment is 3 months. Can stimulate ovulation.
⑦ Bromocriptine: Start with a small dose, 1.25 mg orally each time, for 1 day 2 times. If there is no obvious response after 7 to 14 days, gradually increase to the standard therapeutic dose, that is, take 2.5 mg orally each time, 2 to 3 times a day.
(2) Intra-fallopian tube injection: Used to treat infertility caused by fallopian tube obstruction. Intra-fallopian tube injection of drugs can make the drug directly contact with the fallopian tube lesions and pass through the injection. The pressure generated to separate adhesions usually starts 3 to 5 days after menstruation, once every other day or twice a week, 3 to 5 times per cycle is a course of treatment, rest for 1 month after 2 to 3 courses, and then repeat the treatment. . Commonly used medicinal solutions are:
①Gentamicin:40,000 to 80,000 units each time , dissolved in 20 ml of 0.9% sodium chloride injection.
② Penicillin: 200,000 to 400,000 units each time, dissolved in 20 ml of 0.9% chlorine in sodium chloride injection. A skin test should be done before taking the medicine. Only those with negative skin test can take the medicine.
③Streptomycin: 1 gram each time, dissolved in 20 ml of 0.9% sodium chloride in injection.
④ Dexamethasone: 10 to 25 mg each time, dissolved in 20 ml of 0.9% chlorine in sodium chloride injection.
⑤α-chymotrypsin:5 mg each time, dissolved in 20 ml of 0.9% sodium chloride in injection.
(3) Others: ① Infertility caused by intrauterine adhesions can be treated with estrogen and progesterone cycles. For those with low and thick cervical mucus secretion, estrogen can be administered vaginally. Hormone suppositories, or oral administration of 0.1 to 0.2 mg of diethylstilbestrol, once a day, for 10 consecutive days starting from the 5th day of menstruation. ② Infertility caused by immune factors can be treated with immunosuppressants, with adrenocortical hormones being the first choice.
This article is provided by Baidu Reading and is excerpted from \”The Clear \”Conception\” Plan\” Author: Sun Jianqiu Xie Yingbiao