Perhaps you already know that your wife should take certain medications with caution before and during pregnancy to avoid adverse effects on the fetus, but do you know, expectant father? Before preparing to have a baby, you should also pay attention to taking some medicines carefully, otherwise it may have adverse effects on the future baby.
Research shows that under normal circumstances, there is a protective layer between testicular tissue and the blood flowing through the testicles, which is medically called the blood-testis barrier. This barrier can prevent certain substances in the blood from entering the testicles, but many drugs can pass through the blood-testis barrier and affect the healthy union of sperm and eggs in two ways.
1. Interference with sperm formation
For example, some common immunomodulators, such as cyclophosphamide, nitrogen mustard, vincristine, cisplatin, etc. Drugs have strong toxic effects and can directly disrupt sperm DNA synthesis, including changes in genetic material composition, chromosomal abnormalities, and sperm deformities. There are also morphine, chlorpromazine, erythromycin, rifampicin, antipyretic and analgesics, ciprofloxacin (artificial antibiotic), ketoconazole (antifungal drug), etc. These drugs cause sperm damage by interfering with the synthesis of androgens. Male infertility and habitual miscarriage in pregnant women are partly caused by damage to male sperm.
2. Enter the vagina with semen
Some drugs enter the testicles through the blood-testis barrier, and they can be discharged into the vagina with the semen produced by the testicles during sexual intercourse. , after being absorbed through the vaginal mucosa, it enters the blood circulation in the mother\’s body, which increases the incidence of low-birth-weight babies and fetal abnormalities, and also increases perinatal fetal mortality.
In addition, there are some drugs that can also enter semen, such as metronidazole, ampicillin, amphetamine, diphenylhydantoin, etc., but current research is not very clear about their effects on sperm, fertilized eggs and What are the effects on the fetus?
So,you must use medication carefully in the 2-3 months before pregnancy.
This article is provided by Baidu Reading and is excerpted from \”Complete Pregnancy and Childbirth Plan for Expectant Fathers\” Author: Wang Yanqin