Poor semen liquefaction is a common problem in male infertility

Poor semen liquefaction is a common problem in male infertility

When the semen is first ejaculated outside the body, it is off-white or slightly yellow, and quite viscous. Due to the action of the coagulase secreted by the spermatheca, it quickly condenses into a jelly-like state, and then due to the action of the fibrinolytic enzyme secreted by the prostate, it becomes jelly-like in 5 to 30 seconds. It turns into liquids of different viscosities within minutes, a process called semen liquefaction.

Semen liquefaction can occur outside the body or in the female reproductive tract. Outside the body, the liquefaction time is faster and can usually be achieved within about 5 minutes of ejaculation.

Semen liquefaction is an important process in semen transformation. When the semen is in a coagulated state, the sperm inside remain motionless. Once liquefied, the sperm can move freely in the liquefied environment to run in the cervix, uterus, and fallopian tubes, and eventually combine with the egg to form a fertilized egg. .

If the semen is still not liquefied or is incompletely liquefied 30 minutes after ejaculation, it is said that the semen is poorly liquefied, which will hinder the normal activity of sperm.

Poor semen liquefaction is mainly related to insufficient fibrinolytic enzyme secreted by the prostate. This condition is mainly seen in inflammatory diseases of the prostate and seminal vesicles, and clinically prostatitis and seminal vesiculitis often coexist. Inflammation itself can not only reduce the synthesis and secretion of enzymes, but the pathological process of inflammation can also destroy and inactivate secreted enzymes, leading to the imbalance of the semen liquefaction enzyme system and poor semen liquefaction.

Poor semen liquefaction will not only affect the motility and lifespan of sperm, but also be detrimental to the upward transport of sperm from the vagina to the uterus, leading to male infertility.


This article is provided by Baidu Reading and is excerpted from \”Pregnancy Can Be Simple\” Author: Feifei Mom

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