Male infertility is difficult to treat. What are the difficulties in treatment?

Male infertility is difficult to treat. What are the difficulties in treatment?

Male infertility is a frequent and refractory disease. Overall, the current clinical cure rate is not high and treatment is difficult. The main difficulties are as follows:

(1) Since the causes of male infertility are very complex, and some of the causes have not been fully understood, the current treatments for the specific causes have different effects. Overall, The effect was not very satisfactory. For those with few sperm, low motility, sperm deformity and low semen volume, with traditional Chinese medicine treatment, some patients can be cured and achieve fertility, while some patients can only improve their semen and are still infertile. For such patients, we should not rush for success. We should abide by the law and prescription on the basis of syndrome differentiation and treatment, take time, and review the semen quality regularly. Because the sperm production cycle is long, up to more than 90 days, even if the treatment is effective, it will take several months to show its effect.

(2) For infertility caused by varicocele, some patients can achieve fertility after treatment, but the degree of varicose is above II, the course of the disease is long, and the testicles have become more serious. For those who suffer from damage, it is difficult to achieve the goal of fertility by simple traditional Chinese medicine treatment. For such patients, syndrome differentiation and treatment can be continued on the basis of surgery, and traditional Chinese and Western medicine can be combined to achieve better results.

(3) Idiopathic male infertility is one of the most challenging problems. Traditional Chinese medicine treatment has promising results, but it has not been proven to have a precise clinical effect. For idiopathic oligozoospermia, based on syndrome differentiation, methods of nourishing the kidneys, replenishing essence, activating blood circulation, clearing away heat and detoxifying can sometimes be used to achieve satisfactory results.

(4) Infertility caused by Ureaplasma infection in the reproductive system is considered to be one of the difficulties in treatment because both traditional Chinese and Western medicine lack effective treatments. Although most patients have no clinical symptoms, it is a damp-heat evil that interferes with the sperm chamber, destroys the internal environment of semen, affects the production, maturation and survival of sperm, leading to a decrease in sperm density, sperm motility, and motility. Abnormal changes such as increased deformity rate. Aiming at the etiology and pathogenesis of the disease, you can first use methods of clearing heat, diuresis, and detoxification. Medicines such as Rhizoma Rhizoma, Hedyotis diffusa, Polygonum cuspidatum, Motherwort, etc. can kill Ureaplasma urealyticum. Clinical verification of I over the past few years has confirmed that it can improve semen quality while treating Ureaplasma urealyticum infection in semen.

(5) Immune infertility is also one of the difficulties in treatment. The current treatment effects are not very satisfactory. High-dose hormone pulse therapy has limited efficacy and has high toxic and side effects. Traditional Chinese medicine shows promising signs in treating this disease. For such patients, under the premise of syndrome differentiation, the method of invigorating the spleen and strengthening the surface can be used, and flavored Yupingfeng Powder (astragalus, Atractylodes, Fangfeng, Gypsum, Phellodendron, etc.) can be used to improve the patient\’s allergic constitution. After a period of treatment, anti-sperm antibodies can turn negative.

(6) Azoospermia is a serious and difficult problem in male infertility, and it is difficult to cure in the short term. Among them, congenital absence of the vas deferens and testicular spermatogenic dysfunction are irreversible azoospermia, with almost no hope of treatment. In the case of obstructive azoospermia, some are treatable and some are difficult to treat. However, in recent years, with the development of male surgery, especially microsurgery, more treatment methods have been added. In addition, traditional Chinese medicine can treat it by clearing away heat and promoting dampness, removing blood stasis and nourishing the kidneys.

(7) Congenital testicular agenesis syndrome is caused by chromosomal abnormalities and is mainly characterized by dysplasia of testicular convoluted tubules and hypofunction of Leydig cells. It has not been seen yet. There are reports of successful treatment of this disease. Wuzi Yanzong Pills and Liuwei Dihuang Pills can be used for experimental treatment.

(8) In the treatment of male infertility caused by prostatitis, the method of clearing first and then replenishing or the method of attacking and replenishing should be used according to the priority of inflammatory infertility. For those with severe inflammation, first use heat-clearing and dampness-clearing and diuretic medicines for about 1 month, and then combined with medicines for promoting blood circulation and dredging collaterals, or tonifying kidneys and producing sperms; for those with mild inflammation syndrome of mixed deficiency and excess, medicines for clearing heat and diuresis, promoting blood circulation and dredging collaterals, and tonifying kidneys and producing sperms can be combined. Medicine, the importance of the two depends on the circumstances of the disease. During the treatment, it was also found that many patients were cured of inflammation with heat-clearing and dampness-removing drugs, and their semen returned to normal without using kidney-tonifying and sperm-producing drugs, and their wives became pregnant. Kidney deficiency in inflammatory infertility is more common with qi and yin deficiency, and kidney yang deficiency is extremely rare. Therefore, kidney-warming and yang-improving drugs should be used with caution in inflammatory infertility to prevent them from drying and damaging the essence. In addition, attention should be paid to regulating emotions and cooperating with treatment to facilitate recovery.

(9) The lack of liquefaction of semen is related to the prostate, especially prostatitis. Therefore, treatment should be based on clearing heat, diuresis, dredging collaterals, and nourishing yin. Medicinal treatments such as Phellodendron cypress, Polygonum cuspidatum, Huajie, Coix Seed, Poria cocos, etc., while taking the medicine, it is also necessary to add enzyme-lysing substances, such as malt, hawthorn, etc., for the symptoms of non-liquefaction of semen, especially those that help the spleen and stomach metaplasia. It can regulate the activity of systemic enzymes, which is beneficial to the replenishment of semen liquefaction substances and the recovery of functions.

(10) The treatment of male infertility and sexual dysfunction is based on the principle of clear syndrome differentiation, formulating corresponding treatment rules and selecting prescriptions and medications. Treatment focuses on overall regulation, mainly internal treatment, appropriately supplemented with acupuncture and external treatment methods to eliminate disease pathogens and adjust and restore systemic and local functions.


This article is provided by Baidu Reading and is excerpted from \”The Clear \”Conception\” Plan\” Author: Sun Jianqiu and Xie Yingbiao

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