Fetal paternity testing framework
Fetal paternity testing is a medical testing technology used to identify the biological relationship between children born after maternal pregnancy and the persons involved in the case. This technology mainly relies on DNA sequencing technology and is a very accurate detection method. Before conducting a fetal paternity test, you need to prepare some materials and perform a series of steps.
Material requirements
Performing a paternity test requires collecting accurate samples. These samples include blood samples or oral swabs from the mother and potential father, as well as amniotic fluid samples or placental tissue from the pregnant mother. Among them, blood samples can be collected through the use of intravenous tubes, and oral swabs can be collected through oral brushes. Amniotic fluid samples need to be collected by puncture, while placental tissue needs to be collected during delivery. The collection of the above samples can only be carried out by professional medical personnel to ensure the accuracy and safety of the samples.
Detection process
After completing the sample collection, the next step is to proceed with the testing process. First, the DNA in the sample needs to be extracted and PCR amplified. Their respective DNA is isolated from blood samples or oral swabs of MAT and PAT, and fetal DNA is extracted from the mother\’s amniotic fluid and placenta samples.
The DNA fragments amplified by PCR are separated and compared using electrophoresis, and the parent-child relationship is identified by detecting whether the number and position of STR gene repeat sequences in the DNA are the same.
Explanation of test results
Through the above testing process, the judgment results of parent-child relationship can be obtained. If the DNA match between the child and the mother reaches 100%, it can be determined that the child is the biological child of the mother; if the DNA match between the child and the potential father and mother is high respectively, it will also depend on the genetic differences between them to determine Whether the child is related to the potential father.
Conclusion
Fetal paternity testing is a very accurate testing technology, but it requires the collection of a large number of DNA samples from family members and processing in multiple links to obtain more accurate results. In addition, respecting privacy is also very important. Before each test, the DNA samples obtained must be carefully kept to protect the privacy of the sample owner. In general, fetal paternity testing plays a very important role in solving some parent-child relationship issues.
