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Contents of this article
1. What is the success rate of IVF
The overall success rate of IVF is about 70%-80%, and the success rate is also directly proportional to the age of the woman. It also depends on the analysis of ovarian function and sperm quality. Under normal circumstances, after the age of 35, women\’s physical functions decline rapidly, various hormone levels are secreted abnormally, and the number of basic follicles will also decrease. The quality of follicles is poor, which will affect the success rate of cultivation and further reduce the success rate of transplantation. Even if Even if the transplant is successful, it is easy to miscarry or stop the pregnancy.
2. How to explain China’s IVF success rate ranking
?1 CITIC Xiangya Reproductive and Genetic Hospital – On January 10, 2018, they officially announced that the hospital\’s assisted reproductive treatment cycles reached 44,596 cases. Based on such a huge amount of treatment, the average pregnancy rate of IVF is still as high as 62.4% (1- November). ??Among them, 876 PGD/PGS cycles were performed in 2014, which increased to 2,429 in 2016, an increase of 277% in two years. Among them, PGD accounted for 700 cases in 2016. What\’s more, current research capabilities in this area are still growing. ??In 2017, the hospital performed 3,728 PGD/PGS cycles, 9,485 genetic diagnoses, and 54,215 chromosome tests. ??As the largest assisted reproductive institution in China, CITIC Xiangya performed more than 41,000 assisted reproductive treatment cycles in 2016. According to data from the British Nature magazine, this is equivalent to 1/4 of the annual treatment volume in the United States. The number of pre-implantation tests has increased by 277% in two years. ??2 Reproductive Medicine Center of Peking University Third Hospital Peking University Third Hospital is the leader in IVF in the country. On the official website of Peking University Third Hospital, I changed several keywords: \”test tube baby success rate report\”, \”assisted reproductive pregnancy rate statistical report\”, but I couldn\’t find a success rate statistical report as detailed as CITIC Xiangya\’s. However, there are many news reports about success rates. ??How high is the success rate of Peking University Third Hospital? In an interview, Dean Qiao Jie said that the international average success rate of assisted reproductive technology is around 30% to 40%. The average live birth rate of one embryo transfer cycle in my country is about 25% to 30%. Data released by Peking University Third Hospital in 2013 is that the clinical live birth rate of IVF can reach 30%. ??Looking carefully, we found that CITIC Xiangya’s statistics are clinical pregnancy rates, while Peking University Third Hospital’s statistics are clinical live birth rates. The clinical pregnancy rate refers to the pregnancy confirmed by blood test after transplantation and the presence of gestational sac through B-ultrasound. The clinical live birth rate refers to the successful birth of a child, that is, the successful birth rate. ??So it turns out that if you think about it, clinical pregnancy rate is not scientific as an evaluation indicator for evaluating IVF, because there is a risk of miscarriage after pregnancy, and as the number of ovulation induction cycles increases, the miscarriage rate will gradually increase. Therefore, internationally, the clinical live birth rate/cumulative live birth rate has been used as an effective indicator for evaluating IVF. ??3 Department of Assisted Reproduction, Shanghai Ninth People\’s Hospital??Shanghai Ninth People\’s Hospital is a well-known IVF hospital in the south. The center has a full laminar flow egg retrieval operating room, embryo transfer room, embryo culture room, micro-operation room, semen preparation room, embryo freezing and liquid nitrogen storage room, and is equipped with multiple advanced ultrasound diagnostic machines and embryo experimental operation rooms. Full set of equipment required. ??The public data of the nine hospitals that can be found are relatively early. Data from 2012 show that the thawing survival rate of vitrification-frozen embryos exceeds 99%, and the thawing survival rate of blastocysts is close to 100%. The pregnancy rate in all centers has always remained around 50%, and there is almost no ovarian hyperstimulation. ??In 2013, the number of outpatient visits reached 182,798 per year, and the number of fresh egg retrieval cycles reached 10,250 cycles per year. I believe that the success rate should have improved in these years. ??4 Reproductive Medicine Center of the Sixth Affiliated Hospital of Sun Yat-sen University?? The Sixth Affiliated Hospital of Sun Yat-sen University is a well-known hospital in Guangdong. However, the success rate of the Sixth Hospital of Sun Yat-sen University is based on the pregnancy rate. ??The data in 2017 shows that ≤35 years old, the first cycle means that the patient is relatively young, and the chance of IVF assisted pregnancy is ideal. It is also the best clinical and laboratory standard for testing a reproductive center, such as the Sixth Form Reproductive Center The patient\’s pregnancy rate has always remained above 50%, which is excellent both internationally and domestically. ??The annual average pregnancy rate of frozen blastocyst transfer in 2017 was 72%. The Sixth Form Fertility Center chose the most advanced three-gas incubator for blastocyst culture. After obtaining blastocysts, they were frozen and resuscitated for transplantation, which greatly ensured the patient\’s high pregnancy rate. Rate. ??The annual average pregnancy rate of artificial insemination in 2017 was 12%. The cost of artificial insemination is very small, and the physical and mental burden is also very small. It is an option with higher economic benefits. ??5 Assisted Reproductive Center of Peking Union Medical College Hospital??In the article \”Associated Obstetrics and Gynecology Assisted Reproductive Center Leads Internationally in Clinical Pregnancy Rate\” published by Union Medical College in 2011, the center\’s clinical pregnancy rate reached 51.5% for fresh cycles and 51.5% for frozen cycles. The clinical pregnancy rate reached 73.5%. ??20% in 2004 soared to 20It was more than 60% in 2005 and has been stably maintained at the leading level in China. In 2010, after improvements in resuscitation and transplantation technology, the success rate increased again from 62.1% in 2009 to 73.5%, ranking among the best in the world. ??6 Shanghai Jiao Tong University Renji Hospital Reproductive Medicine Center?? In 2017, the reproductive department of Renji Hospital had 259,520 outpatient visits, 7,898 IVF cycles, IVF clinical pregnancy rate of 56.08%, and FET clinical pregnancy rate of 56.67%. In 2017, the number of clinical IVF cycles completed accounted for 20% of the total number of 17 reproductive centers in Shanghai, and the clinical pregnancy success rate ranked first in the city. ??7 West China Obstetrics, Gynecology and Children\’s Hospital Reproductive Medicine Center?? West China Obstetrics, Gynecology and Children\’s Hospital, also known as West China Second Hospital of Sichuan University, is a well-known assisted reproductive hospital in southwest China. In 1996, preliminary preparations for clinical research on in vitro fertilization and embryo transfer (IVF-ET) began, and an in vitro fertilization-embryo culture laboratory was established, which was officially used for clinical use in May 1997. ??8 Northwest Women and Children’s Hospital Assisted Reproduction Center?? (Shaanxi Maternal and Child Health Hospital)?? In 2017, the number of outpatient visits was 410,000, and more than 14,000 IVF treatments were completed, including 8,397 fresh egg retrieval cycles, freeze-thaw cycles There were 6029 embryonic cycles, and the average clinical pregnancy rate was 62.0%. More than 1,800 artificial insemination cycles have been completed, including 1,140 cases of artificial insemination with husband\’s semen, with a clinical pregnancy rate of 17.7%; and 740 cases of artificial insemination with donor semen, with a clinical pregnancy rate of 27.6%. ??9Shandong University Reproductive Hospital??After more than 30 years of development, it has become an influential clinical, scientific research and talent training base for reproductive medicine at home and abroad. Every year, it attracts more than 400,000 patients with reproductive disorders from all over the country, implements assisted reproductive technology for tens of thousands of people, and the success rate of IVF technology is over 55%. ??10Shanxi Provincial Children\’s Hospital??(formerly Shanxi Maternal and Child Health Hospital Reproductive Medicine Center)??Shanxi Provincial Maternal and Child Health Hospital Reproductive Medicine Center is a key department of Shanxi Provincial Children\’s Hospital and Shanxi Provincial Maternal and Child Health Hospital. It was established in November 2004. , is the only reproductive medicine center in Shanxi Province that can carry out first-, second-, and third-generation IVF at the same time. ??In the news in 2017, Wu Xueqing, head of the Reproductive Medicine Center of Maternal and Child Health Hospital, said that as the human assisted reproduction center in Shanxi Province, the center\’s IVF technology has become more and more mature. ??In 2016, the center completed more than 6,000 IVF cycles, ranking second in North China. Now, the center\’s IVF success rate has exceeded 50%, reaching the national advanced level.
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