Amniotic fluid embolism Amniotic fluid embolism refers to the sudden entry of amniotic fluid into the maternal blood circulation during delivery, causing serious delivery complications such as acute pulmonary embolism, anaphylactic shock, disseminated intravascular coagulation, renal failure, or sudden death. Amniotic fluid embolism is the most dangerous obstetric complication. Since this situation is often unpredictable before delivery, the birth must be closely observed during delivery.