What is non-invasive testing? Non-invasive testing is a non-invasive testing method that can be used to detect chromosomal abnormalities in the fetus. This technology has many advantages over traditional amniocentesis and chorionic villus sampling. The non-invasive test only needs to draw the mother\’s blood. The process is simple, safe and low-cost. Therefore, it has rapidly become widely used in diagnosing fetal chromosomal abnormalities. However, whether non-invasive testing is really reliable has attracted continued public attention. What is the principle of non-invasive testing? The main principle of non-invasive testing is to remove maternal blood from maternal blood through technical means.