Causes of Neonatal Jaundice Neonatal jaundice is one of the most common diseases in the neonatal period, with an incidence rate of more than 60%, seriously affecting the health of newborns. There are many causes of jaundice, which mainly include the following aspects: 1. The liver function of newborns with immature livers is imperfect and cannot effectively metabolize and excrete bilirubin in the body, resulting in excessive accumulation of bilirubin in the body. , causing jaundice. 2. Poor blood circulation. The blood vessels of newborns are relatively fragile and easily damaged, causing blood vessel rupture or bleeding, resulting in poor blood circulation.