Causes of Eczema Eczema is a common skin inflammation with various causes. First of all, family history has a great impact on the occurrence of eczema. If there is a genetic tendency for eczema in the family, the patient will be more likely to develop eczema. Secondly, eczema is closely related to environmental factors, such as pollutants in the air, climate change, food and drugs, etc., which may be causes of eczema. In addition, patients’ living habits are also one of the important factors causing eczema, such as being in tight conditions for a long time.