Detailed explanation of the symptoms of hand, foot and mouth disease. Hand, foot and mouth disease is a viral infectious disease that is mainly manifested by fever, rash in the mouth, palms, soles and other parts of the body. The main modes of transmission are through the respiratory tract, digestive tract and direct contact. The following is a detailed explanation of the symptoms of hand, foot and mouth disease: Fever: Patients often have symptoms such as high fever and general malaise. Oral herpes: Blisters appear on the mucous membranes of the mouth and tongue, and erosions and ulcers may occur during the course of the disease. Palmar and plantar rash: the patient’s palms and soles