The reason for high total bile acid: Total bile acid is one of the important components in bile. It can regulate the functions of the gallbladder and liver in the body and promote fat digestion. However, when total bile acid levels are too high, it can lead to a range of physical problems. So, what causes high total bile acids? First of all, diseases of the hepatobiliary system are an important cause of elevated total bile acids. Such as hepatitis, cirrhosis, cholelithiasis, etc., may