What should I do if I get sick during pregnancy? Can I take medicine? Don’t worry, let’s take a look: Common cold symptoms are mild, such as runny nose, sneezing, etc., which have little impact on the fetus and do not require medication. Just rest for a few days. However, the first trimester (514 weeks) is the period of embryonic development and organ formation of the fetus. If you have the flu and the symptoms are severe, the impact on the fetus will be greater, and taking medicine during this period will also pose greater risks to the fetus.