Hand, foot and mouth disease herpes remission time Hand, foot and mouth disease herpes is a common infectious disease in children. It is caused by a variety of viruses and can cause rashes and blisters in the mouth, hands and feet, etc. The course of the disease varies. During treatment, it is very important to understand the time it takes for herpes to subside so that you can adjust the treatment plan in time to prevent the condition from getting worse. Characteristics of the disease course: There are three main stages in the course of hand, foot and mouth disease herpes: onset period, peak period and regression period. Usually after the disease enters the regression phase, the symptoms will gradually subside, and the course of the disease will show a trend from severe to mild.