Basic overview of hand, foot and mouth disease Hand, foot and mouth disease is a common infectious disease that mostly affects children under 3 years old. Hand, foot and mouth disease is usually caused by enteroviruses, and its clinical manifestations include fever, red spots on the mouth, skin of hands and feet, herpes, and throat discomfort. Hand, foot and mouth disease is a common disease popularized by medical science, so parents should do their best to prevent it. Symptoms of hand, foot and mouth disease The symptoms of hand, foot and mouth disease are relatively obvious and usually include the following symptoms: fever, red spots, and herpes. Symptoms of hand, foot and mouth disease are not limited to