How many days does it take for the herpes of hand, foot and mouth disease to disappear? Hand, foot and mouth disease is a common childhood infectious disease, which mainly manifests as fever, oral ulcers and hand and foot rash. Among them, hand-foot rash is one of the important symptoms of hand-foot-and-mouth disease and one of the most concerning issues for patients. So how many days does it take for the herpes of hand, foot and mouth disease to go away? This article will elaborate on two aspects of treatment methods and precautions. Treatment method Herpes of hand, foot and mouth disease is caused by viral infection, so treatment should focus on symptomatic treatment.