What is the difference between eczema and heat rash? Disease Overview Eczema and heat rash are both common skin diseases, and some people often cannot tell the difference between the two. Eczema is a skin inflammation that is often accompanied by symptoms such as itching, burning, and dry skin. It is common in a wide range of people. Heat rash is a type of rash, which is mainly characterized by red rashes concentrated on a certain part of the skin, often