The efficacy and benefits of the Zusanli acupoint. The Zusanli acupoint is located on the outside below the knee. It is an acupoint frequently used in traditional Chinese medicine and is considered to be one of the most important acupoints in the body. Massaging Zusanli has many benefits for human health. The following will elaborate on the efficacy and benefits of Zusanli acupoint from four aspects. Relieve Fatigue Modern people live a fast pace, have high work pressure, and sit for long periods of time, which can easily lead to fatigue. Massaging the Zusanli acupoint can promote the secretion of endocrine substances in the human body, relieve physical fatigue, and improve the body\’s resistance. This is because the Zusanli acupoint is closely related to the spleen, stomach, liver, and kidneys.