Introduction to the initial symptoms of hand, foot and mouth disease. Hand, foot and mouth disease is an infectious disease caused by a virus and usually occurs in infants and children. The initial symptoms of hand, foot and mouth disease are mild, similar to a cold, including fever, sore throat, loss of appetite and decreased physical strength. However, as the condition worsens, patients may experience mouth sores and blisters on the hands, feet, mouth, and throat. Next, we will introduce the early symptoms and treatment methods of hand, foot and mouth disease from four aspects. Symptoms and examinations in addition to the above