Quit sleeping pills before pregnancy However, if you plan to get pregnant, quit sleeping pills because sleeping pills are very harmful to pregnancy. Sleeping pills damage the physiological and reproductive functions of both men and women. For example, diazepam, chlordiazepoxide, promethazine, etc. can act on the diencephalon and affect the secretion of pituitary gonadotropin. Sleeping pills taken by men can affect fertility by reducing testosterone production, leading to impotence, spermatorrhea and loss of libido. Women taking sleeping pills can affect the function of the hypothalamus and cause changes in sex hormone concentrations. Symptoms of absence of menstruation