Symptoms of premature ovarian failure Premature ovarian failure is a phenomenon of abnormality in the female reproductive system. When this happens, many different symptoms will occur in the female body. Common symptoms include: 1. Abnormal menstruation. Due to problems with ovarian function and abnormal hormone levels in the body, the menstrual cycle may be delayed or advanced. Some people may also experience reduced menstrual flow or irregular cycles, or even symptoms of amenorrhea. 2. Psychological problems: This situation can cause women to have emotional disorders, such as anxiety, insomnia, and depression.