Lupus Erythematosus Causes Lupus erythematosus is an autoimmune disease whose cause is not fully understood. It is currently believed that the combined effects of genetic, environmental and immune factors are the main causes of the disease. First, genetic factors play an important role in the development of the disease. Studies have shown that patients with other autoimmune diseases in their families are prone to lupus erythematosus; secondly, environmental factors can also cause lupus erythematosus, such as pathogenic viruses, infections, ultraviolet rays, etc.; finally, immune factors can also cause lupus erythematosus. An important cause of lupus, because the disease is associated with resistance to