Background: Tang screening is a prenatal screening method used to detect whether the fetus has chromosomal abnormalities and other problems during pregnancy. This kind of examination can help doctors detect fetal problems in time and take appropriate treatment and management measures to ensure the smooth progress of pregnancy and the health of newborns. Next, this article will introduce the relevant knowledge of Tang screening inspection in detail from four aspects: necessity, inspection process, common problems and response methods. Necessity: The necessity of Tang screening examination is to detect fetal chromosomal abnormalities in time. Fetal chromosomal abnormalities include Down syndrome and Edwards syndrome