Background: Blastocyst sex selection has been a controversial topic in recent years. With the rapid development of reproductive medicine, more and more couples choose to screen blastocysts before artificial insemination to determine the gender of the embryo. This article will explore this topic from multiple angles, aiming to provide you with a more comprehensive understanding. Blastocyst gender technology and safety Blastocyst gender selection is performed during the artificial insemination process. It mainly removes a part of the blastocyst cells for genetic testing to determine the gender of the embryo. This technology has been well developed and its accuracy can reach over 95%. However, blastocyst sex selection also has certain safety risks.