The evolutionary mystery behind homologous Robertsonian translocation gene variation. Homologous Robertsonian translocation gene variation refers to the phenomenon of exchange or recombination of partial sequences of chromosomes in the genome. It is a natural phenomenon that widely exists in biological evolution. In recent years, while scientists have conducted in-depth studies of the genetic mutation process, they have also gradually revealed the evolutionary secrets behind this phenomenon. This article will analyze the evolutionary mechanism of homologous Robertsonian translocation gene variation from four aspects: genetics, molecular biology, evolutionary ecology and developmental evolution. Genetic analysis of homologous Robertsonian translocation gene variation is caused by genetic