Where is the Zusanli acupoint? The Zusanli acupoint is one of the most important acupoints in traditional Chinese medicine. It is located on the human foot and has the function of regulating human qi and blood, enhancing human immunity and treating various diseases. The following will introduce the location and use of Zusanli acupoint in detail from four aspects: its location, efficacy, massage techniques and precautions. The Zusanli acupoint is located on the outside of the foot. When the instep is facing upward, draw a straight line from the ankle to the knee. The Zusanli acupoint is located in the middle of this line.