Adrenal gland diseases can cause male sexual dysfunction, oligozoospermia and azoospermia, leading to male infertility. Common diseases include: hypercortisolism, adrenal insufficiency and aldosterone disease, etc. .
(1) Hypercortisolism: Also known as Cushing\’s syndrome, it is caused by the adrenal cortex Caused by excessive secretion of the hormone cortisol. High concentrations of cortisol in the blood can cause loss of sexual desire and erectile dysfunction in male patients; in some patients, blood testosterone levels are reduced, testicular tissue atrophy, sperm production disorders, Leydig cells degeneration and seminiferous tubule fibrosis, eventually leading to infertility. Typical manifestations are: central obesity, moon face, buffalo back, hanging abdomen, supraclavicular fat pad; sanguine appearance, purple skin lines, hirsutism, acne, hypertension and osteoporosis, and abnormal glucose tolerance. Reproductive system manifestations include: loss of sexual desire, erectile dysfunction, testicular softening, and penis shrinkage.
(2) Primary adrenal insufficiency: Primary adrenocortical insufficiency The disease is caused by cortisol or aldosterone deficiency caused by atrophy or destruction of the adrenal cortex. Such patients may experience decreased sexual desire, reduced testosterone synthesis, impaired sperm production, and oligozoospermia or azoospermia. Most patients have erectile dysfunction symptoms that affect their sexual life. In the past, adrenal tuberculosis was the most common cause, accounting for about 80%, but the current incidence has dropped significantly. The occurrence of idiopathic adrenal atrophy is related to autoimmunity, with bilateral adrenal cortex fibrosis and inflammatory cell infiltration; other rare causes include Malignant tumor metastasis, leukemia, fungal infection, radiotherapy damage and double adrenalectomy, etc.
Clinical manifestations:①Aldosterone deficiency group:Due to the body’s storage capacity Decrease and abnormal excretion of potassium and hydrogen ions, causing hyponatremia, hypovolemia, hyperkalemia and mild metabolic acidosis. Manifestations include: anorexia, weakness, hypotension, chronic dehydration, weakness, and weight loss. ②Cortisol deficiency group: can cause anorexia, nausea, vomiting, abdominal pain, diarrhea, bloating, indigestion; weakness, apathy, drowsiness, mental disorder, dizziness, vertigo, hypotension, oliguria, etc. ③Reproductive system: Male sexual dysfunction, loss of libido, erectile dysfunction, and oligozoospermia.
This article is provided by Baidu Reading and is excerpted from \”The Clear \”Conception\” Plan\” Author: Sun Jianqiu and Xie Yingbiao