Can mycoplasma cause infertility? what is the reason?

Can mycoplasma cause infertility? what is the reason?

Mycoplasma is a type of prokaryotic microorganism with a size between bacteria and viruses. There are three types of mycoplasma that are pathogenic to humans. Among them, Ureaplasma urealyticum is a common pathogen of the human urogenital tract and is associated with many urogenital tract infections and perinatal infections. Postpartum infection is related to infertility and is one of the pathogens of sexually transmitted diseases.

Mycoplasma is widely distributed in nature. In addition to humans, many animals such as cats, cows, chickens, dogs, ducks, sheep, horses, rats, monkeys, pigs, pigeons, etc., as well as insects and plants can carry and store this pathogen.

Both Ureaplasma urealyticum and Mycoplasma hominis can be passed from mother to baby during vaginal delivery. In the reproductive tract of infants before 1 year old, the isolation rate of Mycoplasma hominis is 4%; the isolation rate of Ureaplasma urealyticum is 6% in male infants and 38% in female infants. Mycoplasma in the reproductive tract decreases rapidly with age. Mycoplasma can rarely be isolated from the urogenital tract in boys during puberty, while the isolation rate of Ureaplasma urealyticum in girls is 27%, and that of Mycoplasma hominis is 5%. However, after the puberty period, the isolation rate of genital mycoplasma will gradually increase, and it will become more obvious after sexual intercourse.

Chinese scholars conducted Ureaplasma culture on infertile couples in a total of 2181 cases, and 1203 cases were infected, accounting for 55.16%. Among them, 511 were male, accounting for 42.48%; 692 were female, accounting for 57.52%. It can be seen that the infection of this pathogen is common among infertile couples in my country.

Patients with mycoplasma urethral infection may develop symptoms of urethritis and may develop chronic prostatitis. When examining prostatic fluid, active, swimming microbial populations can be seen. Mycoplasma also continues to infect the seminal tract, seminal vesicles and testicles, affecting the quality of sperm and semen, causing infertility. It has been observed that Mycoplasma can cause infertility through the following links.

(1) Interfering with sperm movement:Sperm movement is an important factor for healthy sperm The important function is an important indicator of whether sperm can be fertilized, and the movement of sperm must have a certain speed and frequency. After mycoplasma infects sperm, it often attaches to the head and tail of the sperm, causing the entire sperm to be covered with attachments of varying sizes, causing the sperm to swim weakly and become entangled with each other, leading to infertility.

(2) Increased sperm deformity rate: The increased sperm deformity rate caused by mycoplasma infection is another characteristic of infertility. According to clinical observations, in this type of infertile patients, sperm The malformation rate can sometimes be as high as 80%.

(3) Destroy spermatogenic cells:The curvature of the testicles There are a large number of spermatogenic cells in the seminiferous tubules. These spermatogenic cells develop and reproduce to form sperm. When mycoplasma enters the seminiferous tubules of the testis from the urethra, prostate and other parts, it will destroy the spermatogenic cells and cause the \”spermogenic factory\” to produce inferior sperm. products, leading to infertility.

Therefore, infertility patients should pay attention to check for mycoplasma infection in order to identify the cause and provide symptomatic treatment.


This article is provided by Baidu Reading and is excerpted from \”The Clear \”Conception\” Plan\” Author: Sun Jianqiu and Xie Yingbiao

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