Hello everyone, today I will answer the following questions for you. Many people still don’t know about the causes of chromosomal abnormalities and what to do about chromosomal abnormalities. Let’s take a look at it now. Look!
Contents of this article
- How to check for chromosomal abnormalities
- What causes chromosomal abnormalities in embryos
- What to do about chromosomal abnormalities
1. How to check for chromosomal abnormalities
Generally, you can pass Blood is drawn to check whether there are chromosomal abnormalities. During prenatal check-up, you can check whether there are chromosomal abnormalities through blood and urine tests and a full set of tests. It is best for both husband and wife to have a physical examination to confirm the diagnosis before treatment. Usually, there is no need to go too far. If you are nervous, relax, pay attention to improving your diet, and also need to enhance nutrition.
2. What causes embryonic chromosomal abnormalities
Cause Common causes of chromosomal abnormalities include the following: 1. The mother suffers from diseases or special circumstances, such as colds, fever during pregnancy, advanced maternal age, etc.; 2. Genetic factors, because both parents carry abnormal chromosomes or genes, which may also cause; 3. Exposure to toxic substances during pregnancy, such as large amounts of radiation, chemical substances, etc. Therefore, exposure to the corresponding substances should be avoided during pregnancy.
3. What to do if there are chromosomal abnormalities
1. According to survey data It shows that 1 in every 500 people in the population has chromosomal abnormalities, and there is no gender difference. It can occur in both men and women. Chromosomal abnormalities occur in 5 to 7 in 1,000 live births worldwide. Among them, about half of the children will become patients with chromosomal diseases. In early spontaneous abortion, about 50% to 60% are caused by chromosomal abnormalities. In addition, chromosomal abnormalities are the big boss behind infertility.
2. Chromosomes are the main carriers of genetic material DNA. There are 23 pairs in the human body, of which the first 22 pairs are autosomes and the 23rd pair are sex chromosomes. Use to determine gender. Each pair of chromosomes or genetic elements will separate from each other during cell meiosis and then enter into different cells.In the same daughter cell, different pairs of chromosomes or genetic factors can be freely combined.
3. Chromosomal abnormalities usually manifest as chromosome deletion, translocation, increase in number, duplication, triploidy, etc. The most typical and common chromosomal abnormality is adiploidy, which means that the number of a certain chromosome is only one or three. The most common is trisomy 21 Down syndrome, followed by trisomy 18 Edwards syndrome.
4. Chromosomal abnormalities are very common. Data shows that 45 out of every 100 fertilized eggs have chromosomal abnormalities, which is why even if the uterus is fine, some embryos still fail to implant, or there may be sudden fetal arrest or miscarriage. And 25 out of every 100 fertilized eggs that successfully implant have chromosomal abnormalities, which is why there may be no fetal heartbeat or fetal arrest and miscarriage after implantation.
5. How to prevent chromosomal abnormalities from being passed on to the next generation?
6. Ai Jia Xiaoling said that to solve the fertility problems caused by chromosomal abnormalities, the only way to use technology to screen embryos is the third generation SG Infant PGD technology. In test tubes, female eggs and male sperm are artificially extracted, grown into embryos outside the body, and then implanted into the mother. It can help women with fallopian tube problems leading to infertility and men with low sperm motility and oligospermia and teratospermia leading to infertility. Nowadays, embryos can be screened to select healthy embryos without any disease and then implanted in the uterus. . PGD is very suitable to help screen embryos for chromosomal aneuploidy, help solve infertility or miscarriage caused by embryonic gene abnormalities, and select genes for couples with balanced translocations
This ends the content about the causes of chromosomal abnormalities. I hope it will be helpful to everyone.
