Ferritin? How is ferritin formed?

Hello everyone, many friends don’t know much about ferritin, but it doesn’t matter, because today I will share with you some knowledge about how ferritin is formed. I believe it should be able to solve some of your confusions and problems. If it happens to solve your problem, please pay attention to this site. I hope it will be helpful to you!

Contents of this article

  1. Causes and symptoms of high ferritin
  2. What is the test for ferritin
  3. How is ferritin formed >
  4. Ferritin unit conversion
  5. What is the reason for high ferritin in humans
  6. FT protein noun explanation

1. Causes and symptoms of high ferritin

There are many reasons for high ferritin, including general infections, connective tissue diseases, tumors, especially liver cancer. May cause increased ferritin. Symptoms of high ferritin need to be determined by the actual condition. If it is caused by liver cancer, then there will be pain in the liver area, intermittent dull pain, abdominal pain, etc.; in the early stage of liver cancer, there may only be loss of appetite. Abdominal distention, fatigue, and mild hepatomegaly may appear during B-ultrasound examination; symptoms such as limb weakness, weight loss, general weakness, and easy fatigue may appear in the later stages.

2. What is the test for ferritin

The main purpose of ferritin It is to understand the main storage form of iron in the body. Testing ferritin is also a cancer screening item. If you have any physical abnormalities at ordinary times, you can go to the hospital and actively cooperate with the examination according to your physical condition, but be sure not to worry too much and relax. If you usually have any abnormalities, If you feel unwell, you must treat it symptomatically. You cannot blindly use medication, otherwise it will easily affect your health.

3. How is ferritin formed

What is ferritin? The body\’s stored iron binds proteins that respond to various stimuli.

4. Ferritin unit exchangeCalculation

And 1L=1000mL Ferritin is a widespread iron storage protein with a nanometer-sized hydrated iron oxide core and a cage-like protein shell. Ferritin is a protein containing 20% ​​iron. Normally found in almost all body tissues especially liver cells and reticuloendothelial cells as iron stores. Trace amounts of serum ferritin reflect normal iron stores. Detection of serum ferritin is an important basis for the diagnosis of iron deficiency anemia!

5. What is the reason for high ferritin in the human body

Iron Protein is the most sensitive indicator of iron deficiency in the body. If it is elevated, there are three situations: it may be insufficient utilization of ferritin, and there is a problem with the iron utilization process in the body, resulting in iron accumulation, such as sideroblastic anemia. . Another possibility is that there is a clearance disorder in ferritin. For example, liver disease will lead to elevated serum ferritin. Another possibility is that the synthesis of ferritin is increased. For example, malignant tumors cause ferritin to be synthesized in some parts that should not be synthesized.

6. Explanation of FT protein terms

1. Ferritin ( ferritin (Ft) is a complex of iron-containing proteins with a relatively large molecular weight. Ferritin is spherical, with a core of crystalline iron hydroxide and an outer shell of apoferritin.

2. The storage and release of iron in ferritin are closely related to the redox reaction. When Fe3+ is reduced to Fe2+, iron is released from the ferritin molecule. .

3. Almost all eukaryotic cells can synthesize and contain ferritin. In addition to the liver, spleen and bone marrow in the body, the thyroid, brain, lungs, Ferritin is also found in the pancreas, kidney, myocardium, small intestine, adrenal gland, and placenta. Serum contains trace amounts of ferritin, which is stable under normal circumstances.

4. When iron increases in the body, ferritin can absorb and store iron to avoid excessive intracellular free iron concentration that may cause toxic effects on cells; When the demand for iron in the body increases, ferritin can release iron at any time to supply the body\’s needs. When iron storage and release are out of balance, ferritin changes accordingly. Ferritin is not only an iron storage indicator, but also one of the markers of malignant tumors.

This sharing of questions about how ferritin and ferritin are formed ends here. If your problem is solved,We are very happy.

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