Gamete intrafallopian transplantation, do you know?

Gamete intrafallopian transplantation, do you know?

Gamete intrafallopian transplantation (GIFF) means that mature eggs (taken from the ovaries) are washed and processed together with sperm, and then directly implanted laparoscopically into the fallopian tube, the site of natural fertilization. One advantage of this method is that it has a higher success rate (lower failure rate) than intrauterine implantation of fertilized eggs. If the fertilized egg travels normally through the fallopian tube to the uterine cavity, then there is more reason to believe that the synchronization of the endometrium is ready.

Laparoscopy for gamete intrafallopian transplantation can also be done on an outpatient basis but requires general anesthesia. In order to place the laparoscope or other instruments, 3 small incisions need to be made. If you choose this method, the abdomen is inflated so that the organs inside can be separated and the doctor can see the ovaries and fallopian tubes. Fine needle puncture is used to aspirate the eggs and surrounding fluid from each mature follicle. The aspirated eggs are separated from the fluid while the patient is still anesthetized; they are then combined with the cleaned sperm placed in the catheter. At the same time, the doctor must determine whether the patient\’s fallopian tubes are smooth and healthy. This combination is then implanted into 1 or 2 fallopian tubes. The incision in the abdomen is closed with 1 or 2 stitches, and after a few hours of rest in the lounge, you are ready to go home. Likewise, take it easy for a week or two while avoiding strenuous activities. If you have abdominal pain or if there is residual gas in your body, which often causes shoulder pain, you should see your doctor to see if you need to take some painkillers. In fact, it\’s a good idea to ask your doctor for some pain relief medication when you leave the hospital.

In the early days, when the success rate of in vitro fertilization was not high, other assisted reproductive technologies were chosen. The experts who invented gamete intrafallopian transplantation discovered that if eggs and sperm are implanted into the fallopian tubes in a natural environment as early as possible, the pregnancy rate may be improved. As the success rates of IVF continue to improve, the two methods currently have almost the same success rate. However, few patients use gamete intrafallopian transplantation, mainly because it requires surgery and general anesthesia, and it is more expensive and risky than in vitro fertilization.

Because this technology helps sperm pass through the vagina, uterine cavity and uterus, it is especially suitable for patients with oligospermia, no sperm, or sperm movement disorders. However, its success rate is still low, and this technology is only limited to a few large medical centers and requires further research and promotion. Despite this, gamete intrafallopian transplantation is still a more promising treatment method than in vitro fertilization.


This article is provided by Baidu Reading ExcerptFrom \”The Clear \”Conception\” Plan\” Author: Sun Jianqiu and Xie Yingbiao

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