How to treat infertility caused by oligozoospermia?

How to treat infertility caused by oligozoospermia?

It is generally believed that oligospermia occurs when there are less than 20 million sperm per milliliter of semen. Oligozoospermia can often cause infertility, which is easy to understand. Because there are fewer sperm, there are fewer opportunities to meet the egg. But I have encountered this situation in the clinic: a man with oligozoospermia who has only 3 million to 5 million sperm per milliliter of semen, but his wife is pregnant. The husband was deeply suspicious and asked the doctor: How could his wife be pregnant? Are there “other circumstances”? What needs to be pointed out here is that infertility with oligozoospermia is not absolute. If the sperm count is low and the quality is particularly good, it is still possible to have children. Of course, if the sperm count is low and the quality is poor, it will be difficult to have children.

The common cause of oligozoospermia is that the testicles have poor sperm production function and produce a low number of sperm. The testicles of such people are small in size and soft to the touch; there are also some patients with oligozoospermia whose testicles are normal and can produce enough sperm, but the tubes that transport the sperm are not completely smooth and cannot drain them all out. This results in oligozoospermia. There are also a small number of young people who are caused by excessive sexual life. They mistakenly believe that increasing the frequency of sexual intercourse will increase the chances of having children, but contrary to their wishes, it causes oligospermia.

Treatment of oligozoospermia should be based on the cause. Therefore, when the doctor asks about the medical history, the patient should cooperate with the doctor to explain his condition or reasons in detail, and correct certain bad living habits according to the doctor\’s advice, such as not smoking, drinking less, not wearing tight pants, etc. For those with poor testicular spermatogenic function, some Chinese or Western medicine can be used to enhance the sperm-producing function of the testicles. If the vas deferens duct is not smooth enough, it is mostly due to incomplete obstruction caused by inflammation. It is necessary to use drugs to eliminate the inflammation and absorb or remove the blocked inflammatory products to make the duct completely unblocked. If it is caused by too frequent sexual intercourse, the frequency of sexual intercourse should be appropriately reduced. If the sperm count is low and the semen volume is large, artificial insemination can also be performed after the semen is concentrated, or the semen ejaculated several times can be refrigerated, and then artificial insemination can be performed concentratedly.

Treatment should be based on different causes of oligospermia, and different treatment methods should be selected:

(1) Treatment of oligospermia caused by endocrine dysfunction: Some patients can increase sperm count by taking clomiphene, 25 mg daily, 25 days a month, and then stop 5 days, 12 months is a course of treatment. There are reports, long-term use can reduce the percentage of sperm with normal morphology, so low-dose therapy is currently recommended, that is, 25 mg every other day. Human chorionic gonadotropin 1,000 units is also used, intramuscularly injected twice a week, with a 10-week course of treatment; at the same time, 100 to 200 mg of vitamin E can be taken orally every day for 3 to 4 months. Testosterone propionate 50 mg was also tried, intramuscularly injected 3 times a week for 3 months. The sperm count decreased or disappeared during the medication, and a rebound phenomenon occurred after the medication was stopped. However, it was reported that the effect was not good. Recently, it was reported that using ketotifen 1 mg twice a day for 3 months significantly improved sperm density and motility. Pentoxifylline can increase the motility of sperm with insufficient motility in idiopathic oligozoospermia when added to semen or taken orally.

(2) Varicocele is the most common cause of oligozoospermia, with reports as high as 39%. Varicocele ligation can be performed. One year after surgery, sperm density increases in 50% to 80% of cases, and the wife becomes pregnant in 30% to 50% of cases.

(3) Reproductive tract inflammation such as acute and chronic orchitis, epididymitis, prostatitis and seminal vesiculitis can also cause rare diseases. Common causes of spermatosis. For treatment, carbenicillin can be used 4 grams per day, divided into 4 times, and used continuously for 1 month. Compound sulfamethoxazole can penetrate into the prostatic fluid and has good efficacy. It can be taken 2 times a day, 2 tablets each time, for 3 months.

(4) Supplementing trace elements: Zinc supplementation has certain effects on oligospermia and dead sperm. , the sperm count increased significantly after taking the medicine. Due to the antagonistic effect of zinc and copper, zinc supplementation also treats high copper. The treatment method is to take 50 to 100 mg of zinc gluconate orally each time, twice a day, and a course of treatment is 3 months. Zinc sulfate is also used for treatment.

(5) Arginine supplement: Arginine is a necessary component for sperm production. Less The amino acid content in the semen of patients with spermatozoa is significantly lower than that of normal men. Supplementing arginine, 4 grams orally per day for 10 weeks, can improve sperm count.

(6) Chinese medicine can be tried: Wuzi Dihuang Decoction: 9 grams of wolfberry, dodder, raspberry , 12 grams each of Plantago, 45 grams of Schisandra, 12 grams each of Alisma, Angelicae, and Poria, 45 grams of licorice, yam, paeoniae, and white peony root., Rehmannia glutinosa, and Codonopsis pilosula 12 grams each. Decoction in water, 1 dose per day, 100 doses is a course of treatment. After treatment, the fertility rate of those with abnormal semen can be restored to 56%.


This article is provided by Baidu Reading and is excerpted from \”The Clear \”Conception\” Plan\” Author: Sun Jianqiu and Xie Yingbiao

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