What are the causes of infertility in couples?

What are the causes of infertility in couples?

Infertility is caused by both parties in approximately 20% of cases. Maybe the couple is eager to have a child, or the pressure from relatives and friends around them makes the couple often anxious and nervous. Sometimes, even the couple themselves are not aware that they are in this tension. Excessive mental stress and anxiety can cause a series of physiological changes that affect pregnancy, such as reduced sperm production, ovulation disorders, and fallopian tube problems. This problem is more prominent among couples over 30 years old. The more pressure and tension the couple feels, the more \”mission impossible\” the pregnancy becomes. Don\’t think that psychological disorder is a minor problem. In fact, in many cases, it is very fatal. If the couple cannot \”unload\” their psychological \”burden\”, it is better to seek help from relevant professionals. Behavioral therapies that help the mind and body relax, such as massage, yoga, or meditation, often help.

The cause of infertility in most couples comes from either the wife or the husband. Howeverfor some couples, both parties are capable of having children, but their union may be the cause of infertility. This situation is elusive and difficult to explain medically. For example, immune problems in pregnancy are not yet understood. Any of the following three situations can explain the wife\’s rejection of her husband\’s sperm. ① Cervix: Sperm and cervical mucus repel each other. ② Fallopian tube: During the fertilization process, the sperm and egg cannot live in peace. ③Uterus: When sperm passes through the uterus, it cannot be capacitated.

The mechanism of sperm capacitation has not yet been elucidated. It is speculated that it may be an immune response process. Experiments on rabbits in 1951 showed that sperm entering the vagina does not have the ability to fertilize. It is only after certain substances in the uterus or fallopian tube activate sperm acrosome enzyme that the sperm has the ability to fertilize. This process is called capacitation. Before capacitation, the sperm must penetrate the egg\’s coat, a process that can be clearly observed in experiments. It is an active and harmonious process.

A variety of proteins contained in semen can be used as antigens to induce abnormal immune responses in women, and then produce antibodies in the blood or locally in the reproductive tract. Such antibodies have agglutination or braking effects on sperm, making sexual intercourse Sometimes it interferes with sperm function. 15% to 20% of infertile couples cannot find the cause through systematic examination. Anti-sperm antibodies are found in the serum or cervical mucus of these women through immunological examination. The reason why a wife develops antibodies to her husband\’s sperm is unknown. It may be that the body mistakes sperm for sperm.come invaders and produce killer antibodies or prevent sperm from entering the uterus through the cervix. Anti-sperm antibodies can be detected in blood tests or in cervical secretions. Semen contains a variety of proteins as antigens, which produce an immune response after being absorbed by the cervical epithelium. Anti-sperm antibodies are produced in the woman\’s blood or part of the reproductive tract. During sexual intercourse, anti-sperm antibodies cause sperm to agglutinate and lose their motility, affecting pregnancy. Under normal circumstances, women do not produce antibodies due to the masking and inhibitory effects of enzymes and a series of immunosuppressive factors in the seminal plasma and the regulatory effects of the local immune system in the female reproductive tract. When the reproductive tract mucosa is damaged or during menstrual intercourse, semen can enter the blood or sperm antibodies can be detected in the cervical mucus. Patients with anti-sperm antibodies should be advised to wear condoms during sexual intercourse to avoid contact between sperm and the female body. As the body avoids the stimulation of antigens, the antibodies in the body gradually disappear. For this reason, the blood antibody titer must be dynamically observed. When the titer drops and the sperm can pass through the reaction site without being damaged, the use of condoms can be cancelled. If the couple passes the above-mentioned \”examinations\” and finds that there are no problems, perhaps all the couple needs is more time and a timely \”try.\” The wife can continue to take ovulation tests to choose the best time to conceive.

Not having sexual intercourse during ovulation will prevent sperm and eggs from meeting each other, affecting conception, or having sexual intercourse too frequently will affect the quantity and quality of sperm. The reason for the inability to conceive may be as simple as not having sexual intercourse during the wife\’s ovulation period. Other obvious abnormalities include: too frequent or too few sexual intercourses. Therefore, it is necessary to learn relevant sexual knowledge, including basic knowledge of sexual reproductive physiology, and learn how to monitor ovulation. Consult a sexologist if necessary.


This article is provided by Baidu Reading and is excerpted from \”The Clear \”Conception\” Plan\” Author: Sun Jianqiu and Xie Yingbiao

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