Indications for artificial insemination by sperm donors include oligozoospermia, tendency to genetic diseases, history of exposure to toxic substances such as dioxins, or both parties having infertility factors or Rh blood type incompatibility or long-term unexplained infertility disease patients.
Advantages of artificial insemination with sperm donors:
①The child is at least biologically related to the mother;
②Sperm banks can Provide sperm donors with a variety of physical characteristics to provide more opportunities to match the father\’s physical characteristics, such as height, body shape, eye or hair color and ethnic background;
③ Will the donor The sperm of the sperm donor is frozen for future use, so that the same patient can have multiple children with the same blood relationship;
④ The pre-screening technology used in artificial insemination of sperm donors can exclude many Hereditary diseases, such as familial amaurosis, etc.
Disadvantages of artificial insemination with sperm donors:The main reason is that the couple does not know who the sperm donor is and whether they have undergone multiple screening tests, especially if it is donated to a small private hospital. sperm donor. Most reputable sperm banks are relatively careful in all aspects of inspection, but there is still no complete guarantee. Although the incidence of genetic diseases in children born through artificial insemination by donors is lower than that in children conceived naturally, it is theoretically believed that as the application of artificial insemination by donors increases, the incidence of genetic diseases in children will increase accordingly. rise. Couples who receive artificial insemination from donors must sign and agree to bear the risk of abnormality in their children; there are also issues of cross-infection of sexually transmitted diseases, including AIDS (HIV). Therefore, it is important to further screen sperm donors for sexually transmitted diseases to minimize their risk.
In addition, it can also be found that the cost of screening for genetic diseases is very high, but any couple believes that the sperm bank or the attending doctor must fully investigate the genetic background, including family history of genetic diseases and Analysis of cellular chromosomes.
For couples undergoing artificial insemination with donor sperm, it is not excessive to request a copy of the donor\’s family genetic history. The attending physician must ask the sperm donor to fill out a genetic family history form. You can learn about the source of sperm and the artificial insemination process, who is the most representative sperm donor, how old the sperm donor is, what screening tests for infectious diseases have been done, and whether the semen is fresh or frozen (frozen) Semen is easier to screen).
Physicians may prefer to use cryopreserved sperm from sperm banks, becauseBecause they have more advantages, especially in terms of more detailed examination or screening, before sperm is cryopreserved, it is necessary to conduct a comprehensive quality analysis and sexually transmitted disease examination (including HIV) and understand the history of genetic diseases. The main disadvantage of using frozen sperm is that the pregnancy rate is lower than that of fresh semen. Fresh semen can survive for 48 hours after artificial insemination, while the sperm motility of frozen semen is reduced and can only survive for about 24 hours. Therefore, it is particularly important to determine the time of ovulation (that is, the time of artificial insemination). Studies have shown that if ovulation is timed accurately, the success rate of artificial insemination with frozen semen will be the same as that with fresh semen.
This article is provided by Baidu Reading and is excerpted from \”The Clear \”Conception\” Plan\” Author: Sun Jianqiu and Xie Yingbiao