What is intracytoplasmic sperm injection? Do you understand?

What is intracytoplasmic sperm injection? Do you understand?

If infection control and surgery cannot solve the problem of too few sperm, no sperm, or insufficient sperm capacity during ejaculation, a new technology can currently solve the problem of male infertility. Intracytoplasmic sperm injection (ICSI) is the injection of a single sperm into an egg through a microinjection. It can make men with oligozoospermia or azoospermia become fathers.

If there are sperm in the semen, but the number is not enough to bind to the egg through normal pathways, the sperm can be collected from the semen. If there are no sperm in the ejaculate, sperm can be obtained from the epididymis or testis by acupuncture. If that fails, the next step is to remove some of the sperm-producing tissue from the testicles in order to obtain sperm from it.

Acupuncture sperm extraction takes about 30 minutes or more. If the urologist needs to extract sperm from the sperm-producing tissue, the whole process takes 1 hour. These procedures are performed on an outpatient basis with the patient under local or general anesthesia. After the sperm is obtained, one sperm can be injected into the collected mature egg, and the fertilized egg can be placed in the culture medium to develop into an embryo.

After acupuncture for semen extraction, the patient can recover from the anesthesia quickly. The adverse reactions are minimal, but there will be some pain and discomfort in the next day or two. Applying ice can reduce the chance of inflammation. Try to avoid heavy physical activities within 1 week, and try not to do strenuous work, such as transportation work, within 1 month.

Intracytoplasmic sperm injection allows almost all men with oligozoospermia to have enough sperm to inject into their eggs. Among the patients who have no sperm at all in their semen, about 50% have sperm in their testicular tissue.

Studies show that the success rates of attempts to use intracytoplasmic sperm injection are 33% and 42% respectively. Intracytoplasmic sperm injection is currently considered a leading technology for the treatment of severe male infertility. The success rate of pregnancy mainly depends on the quantity and quality of fertilized eggs.

While intracytoplasmic sperm injection may offer hope to infertile patients who long for children, the technique is not without risks. If the lack of sperm is due to genetic reasons, the father may pass the disease on to his son. Among men with azoospermia, gene deletion on the Y chromosome causes infertility in 15% to 20% of men. The Y chromosome determines male gender. A baby boy born to a man with a missing Y chromosome gene will suffer from infertility like his father when he grows up. My daughter doesn’t have this kind of thingRisk because she inherited her father\’s X chromosome instead of his Y chromosome. Y chromosome gene deletion is spontaneous. Before the advent of intracytoplasmic sperm injection technology, men with this disease were infertile and therefore could not pass the missing gene to the next generation.

Intracytoplasmic sperm injection may pass the gene deletion to male babies. When male babies with this gene deletion grow up, they can also have children using intracytoplasmic sperm injection.

If a male infertile patient has normal testicles but no sperm during ejaculation, then the possibility that he will be born without a vas deferens is small (1% to 2%). In this case, intracytoplasmic sperm injection can also be tried. Most men who are born without vas deferens also carry the cystic fibrosis gene. Men with this disease usually die before reaching adulthood. A man who carries the gene but does not have the disease may pass it on to the next generation if his spouse also carries the gene.


This article is provided by Baidu Reading and is excerpted from \”The Clear \”Conception\” Plan\” Author: Sun Jianqiu Xie Yingbiao

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