Which parents are at risk of having offspring with genetic diseases?

Which parents are at risk of having offspring with genetic diseases?

According to statistics from geneticists, the following parents are at risk of being born with serious genetic diseases.

(1) First-time mothers over 35 years old: Data show that the probability of accidental chromosomal errors increases significantly in the later reproductive years, because since a woman is born, the ovaries have All her lifetime egg cells are stored. As she gets older, her eggs become relatively older and the chance of chromosomal errors increases. Therefore, the likelihood of having a child with a chromosomal abnormality increases accordingly.

(2) One of the parents is a balanced translocation chromosome carrier:If one of the couple is found to be a balanced translocation chromosome carrier through chromosome examination, you can consider not having children. Or perform prenatal genetic diagnosis after pregnancy to prevent the birth of affected children.

(3) Couples with a history of habitual abortion:According to statistics, the probability of chromosomal abnormalities in pregnant women with a history of habitual abortion is several times higher than that of the average person. If a woman has a history of spontaneous miscarriages, her husband often has a similar genetic defect.

In this way, the fetus inherits the defective gene from its parents, and is twice as likely to suffer from genetic diseases as a normal fetus. Based on this, medical scientists believe that the biochemical sensitivity in the mother\’s body may be able to identify genetic defects in the fetus. Therefore, this magical power of natural laws can naturally abort unqualified fetuses. Therefore, couples with a history of habitual miscarriage should undergo detailed physical examination and genetic counseling for both parties before becoming pregnant again.

(4) Mothers who have given birth to children with Down syndrome: The probability that their second child will be a child with Down syndrome is 2% to 3%. Pregnant women who have given birth to a child with an autosomal recessive metabolic disease (such as albinism, congenital deaf-mute, dwarfism, etc.) may have a 25% risk for the next child.

(5) The mother is a patient with a severe sex-linked disease (such as hemophilia): All sons are patients with the disease, and the daughter becomes a carrier of the disease gene .

(6) Workers who are often exposed to radiation or chemical agents.


This article is provided by Baidu Reading and is excerpted from \”The First Three Months of Pregnancy – Pregnancy Preparation Period\” Author: Wang Liru

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