Why is the abortion rate of IVF so high (discuss the embryonic development issues of IVF in detail)

Why is the abortion rate of IVF so high

In vitro fertilization has become one of the hopes for infertile couples. However, fetal failure also occurs from time to time. Why is the abortion rate of IVF so high? It will be discussed in detail below from four aspects: embryonic development process, viral infection, genetic factors and maternal age.

Embryonic development process

Embryonic development is one of the main causes of IVF fetal failure. Because in the early stages of embryonic development, the embryo needs to divide from single cells to multi-cells, and then differentiate into organs such as heart, liver, kidneys, etc. During this process, the genes of some embryos mutated, causing problems in the development of fertilized eggs. In addition, inaccurate timing of embryo division can also lead to problems with embryo development, which are one of the reasons for fetal arrest in IVF.

Viral infection

Viral infection is also a cause of fetal arrest in IVF. Some viruses, such as rubella virus and herpes simplex virus, can also infect the fetus through the placenta when pregnant women are infected. These viruses can disrupt fetal development and cause in vitro fertilization to stop. Therefore, adequate virus screening before IVF embryo transfer is also very important to prevent IVF fetal arrest.

Genetic factors

Genetic factors are also one of the reasons for fetal arrest in IVF. If the couple has certain genetic problems, these problems will also be passed on to the embryo, causing abnormal embryo development or genetic diseases. These situations may lead to discontinuation of IVF. At the same time, if the embryo\’s chromosomes are abnormal, it may also lead to termination of pregnancy.

Age of pregnant woman

Maternal age is also a reason for IVF fetal arrest. As a woman ages, the quality of her eggs deteriorates and therefore embryonic development is affected. In addition, as women age, their likelihood of suffering from some diseases also increases, such as high blood pressure, diabetes, kidney disease, etc. These diseases will have adverse effects on the embryonic development of IVF.

Summary

To sum up, there are various reasons for discontinuation of IVF, including embryonic development problems, viral infection, genetic factors, and maternal age. A comprehensive examination and evaluation should be carried out before IVF operation to prevent various accidents and ensure the safety of mother and baby.

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